The main research theme of the unit concerns the characterization of the integrated functioning of the cell and in particular understanding the processes, which, at the molecular level, govern the organization and the overall physiology of the cell.
Researchers carry out their work on different organisms (from viruses to human cells) or on complexes reconstituted in vitro, at different scales and under various physiological conditions. The common objective of this work is modelization of the global functioning of model and non-model organisms and ultimately to predict the impacts of molecular, subcellular and environmental changes on the behavior of normal or pathological cells and tissues.
The total number of staff in the unit generally varies between 600 and 700 people depending on the presence of short-term internships (<1 year).
As of January 1, 2021, the unit has 399 permanent staff and 220 non-permanent staff.
Each of the 60 research groups belong to one of the 5 disciplinary departments.
Thématiques de recherche
Thématiques:Architecture and Dynamics of cellular structures and associated pathologies
Processing of genetic information and its dysfunctions
Host-microbe interactions: infectious diseases and symbiosis
Bio-inspired engineering for energy, health and the environmentMoyens humains et matériels
Moyens humains:A team of about 15 people, including 4 researchers, specialised in the study of plant-bacteria interactions
Moyens matériels:Sequencing (Next generation sequencing)
Structural biology (Crystallisation, NMR, CryoEM)
Bioimaging (Cytometry, Electron Microscopy)
Proteomics (Mass Spectrometry)
Biophysique (Electronic Spectroscopy, Resonance Raman & FTIR)Services aux entreprises